NCT00905697: Long-term follow-up of living lung donors

NCT00905697 is Kyoto University's prospective follow-up of living lung donors—not of lung-transplant recipients. The observational registry records 40 actual donors. Its central question was how donation affected the donor's subsequent physical and psychological well-being. 1 2

Assessments included patient-reported health status and quality of life, respiratory symptoms such as breathlessness, psychological symptoms and sleep-related measures. The planned follow-up extended annually over five years. These outcomes capture aspects of donation that survival statistics alone would miss. 2

The cited registration establishes the donor population, longitudinal design and planned measurement domains, but it does not supply a verified numerical pre/post-donation quality-of-life difference or a comparison with non-donors. Consequently, it cannot be used to promise that lung donation has no lasting symptoms, nor can recipient improvements be substituted for donor outcomes. 2

Sources

1. ClinicalTrials.gov — ClinicalTrials.gov — NCT00905697. Original registration; establishes the exact study identity and registered methods.Original study registration · Original record checked against the registry API. Checked 2026-10-10. Registration and current registry fields do not by themselves establish efficacy. Historical details in the article retain their stated date. Supplied note: ClinicalTrials.gov — NCT00905697. Original registration; establishes the exact study identity and registered methods.

2. ICH GCP — ICH GCP — NCT00905697. Readable reproduction of the sponsor-submitted registration, including the design and dated status fields; not an independent outcome study.Cited supporting source · Link and description preserved from supplied research. Checked in supplied research dated 2026-10-10. Source description comes from supplied research; underlying page was not independently re-read for this update.