NCT00632515: Family communication about colorectal-cancer risk

This was an observational study of colorectal-cancer risk communication and screening behavior within families. MD Anderson studied patients diagnosed with colorectal cancer by age 60 and their first-degree relatives aged at least 40. The intended sample was up to 325; the final registry lists 269 actual participants, with completion in June 2020. 1 2

A 30–45-minute telephone questionnaire assessed knowledge, attitudes, family communication, provider interactions, and screening behavior, particularly colonoscopy adherence. Known hereditary colorectal-cancer syndromes and inflammatory bowel disease were excluded under the protocol. 1 2

The research question is which psychosocial and access factors accompany family communication and screening—not whether a new cancer drug works. Because the design is cross-sectional, an association would not by itself prove causation. No numerical association estimates were independently verified here. 1 2

Sources

1. ClinicalTrials.gov — ClinicalTrials.gov — NCT00632515. Original study registration: sponsor, design, population, endpoints and dated history.Original study registration · Original record checked against the registry API. Checked 2026-10-10. Registration and current registry fields do not by themselves establish efficacy. Historical details in the article retain their stated date. Supplied note: ClinicalTrials.gov — NCT00632515. Original study registration: sponsor, design, population, endpoints and dated history.