NCT00223522: Measuring antipsychotic adherence against electronic monitoring

Medicine Signal Editorial Desk
Updated 2026-10-10

Registry status when checked 2026-10-10Completed

Study: Accuracy of patients' self-reports and clinicians' impressions of oral antipsychotic adherence in schizophrenia or schizoaffective disorder, associated with the University of Texas Health Science Center at San Antonio. 1 2

Design and measurements: The protocol planned 50 participants followed for 12 weeks. Subjective assessments were compared with electronic medication-container monitoring, pill counts, and selected blood drug measurements. Patient and clinician assessments occurred at baseline and follow-up; pill counts were repeated every two weeks. 1 2

What is established: The historical record is completed. No sensitivity, specificity, correlation, or rate of overestimated adherence was verified. Electronic container opening is also not identical to demonstrated ingestion. This is a study of measurement accuracy, not a randomized trial proving one antipsychotic more effective than another. 1 2

Sources

1. ClinicalTrials.gov — ClinicalTrials.gov — NCT00223522. Original study registration: sponsor, design, population, endpoints and dated history.Original study registration · Original record checked against the registry API. Checked 2026-10-10. Registration and current registry fields do not by themselves establish efficacy. Historical details in the article retain their stated date. Supplied note: ClinicalTrials.gov — NCT00223522. Original study registration: sponsor, design, population, endpoints and dated history.

2. ICH GCP — ICH GCP — readable reproduction of the sponsor-submitted ClinicalTrials.gov record. Supports the registration details quoted here; not an independent clinical-results publication.Cited supporting source · Link and description preserved from supplied research. Checked in supplied research dated 2026-10-10. Source description comes from supplied research; underlying page was not independently re-read for this update.