NCT00140439: IMPACT DC: asthma follow-up after an emergency visit

NCT00140439 is IMPACT DC, a randomized trial of an emergency-department-based follow-up clinic for children with high asthma morbidity. Teach and colleagues randomized 488 children aged 1–17, 244 per group, to a comprehensive clinic visit or an educational booklet/control condition. The visit addressed self-management, environmental triggers and links to ongoing care. 1 2

172 of 244 intervention patients (70.5%) attended. Over six months, adjusted mean unscheduled asthma visits were 1.39 with intervention versus 2.34 with control; relative risk 0.60, 95% CI 0.46–0.77. This is direct evidence of reduced unscheduled use, not merely a planned endpoint. 2

At six months, reported inhaled-corticosteroid use in the preceding two days was 49.3% versus 26.5%, and selected quality-of-life measures also favored intervention. The result concerns a bundled follow-up service in this high-morbidity urban population; it does not isolate which component caused the improvement or demonstrate the same effect in every healthcare setting. 2

Sources

1. ClinicalTrials.gov — ClinicalTrials.gov — NCT00140439. Original registration; establishes the exact study identity and registered methods.Original study registration · Original record checked against the registry API. Checked 2026-10-10. Registration and current registry fields do not by themselves establish efficacy. Historical details in the article retain their stated date. Supplied note: ClinicalTrials.gov — NCT00140439. Original registration; establishes the exact study identity and registered methods.

2. Teach, Crain, Quint, Hylan and Joseph (2006). Improved Asthma Outcomes in a High-Morbidity Pediatric Population: Results of an Emergency Department–Based Randomized Clinical Trial. Archives of Pediatrics & Adolescent Medicine 160(5):535–541; DOI 10.1001/archpedi.160.5.535. Original full text, abstract and outcome tables — Teach, Crain, Quint, Hylan and Joseph (2006). Improved Asthma Outcomes in a High-Morbidity Pediatric Population: Results of an Emergency Department–Based Randomized Clinical…Cited supporting source · Link and description preserved from supplied research. Checked in supplied research dated 2026-10-10. Source description comes from supplied research; underlying page was not independently re-read for this update.